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Tularemia -Draining Lesion (Rabbit fever, Deer fly fever, Ohara Disease, Francis Disease) – CATEGORY A

JHH Precautions/Isolation Category CDC Precautions/Isolation Category
Standard Drainage and Secretion

May stop additional isolation when:
lesion no longer drains

Symptoms
Local ulcer and regional lymphadenophathy, fever, chills, headache, malaise, substernal discomfort, prostration, weight loss, and no production cough.

Comments:
Tularemia is caused by a small gram-negative coccobacillus, Francisella tularensis. Two serotypes, Jellison type A and Jellison Type B, are recognized. Jellison Type A has much higher mortality (5-15%) than Type B, which rarely causes fatalities even in untreated cases. Disease manifestation relates to mode of exposure.

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Incubation Period
1-14 days, usually 3-5 days. Route and dose dependant.

Period of Communicability
No person to person transmission. Numerous wild animals are the reservoir. Flies are infectious for up to 2 weeks, ticks are infectious for life, in blood, two weeks and in lesions, 1 month. Label all cultures sent to prevent exposure in the lab. Lab personnel must work under a hood in the lab.

Cohort (Inf. with Inf./Exp. with Exp./Non-Exp. with Non-Exp.)
Not Required

Transport Issues
Carefully label all cultures sent to prevent exposure in the lab

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Who’s susceptible
General. Infection produces protective immunity. However, re-infection can occur

Who’s exposed
By bite of an arthropod (ticks, deer flies, and mosquitoes). Skin or mucus membrane exposure to contaminated water, handling infected material or animals, such as rabbits, food, or inhalation of contaminated dust.

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Exclusion of symptomatic personnel from duty
Yes, until fit to work.

Exclusion of exposed susceptible personnel from duty
Not Required

Isolation of exposed susceptible asymptomatic patients
Not Required

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Prophylaxis for exposed
Doxycycline 100 mg PO BID x 14 days or Ciprofloxin 500 mg PO BID

Treatment for the Ill
Gentamycin 5 mg/kg IM or IV qd or Streptomycin 1gm IM BID (if available) or Doxycyline 100 mg IV/PO BID. Treat for 10-14 days.

Military/Institutional Populations Special Issues
Use repellent and nets, check for ticks. Can be aersolized and used as a biological warfare agent.

Contact Local Health Dept Yes
Contact HEIC Yes

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